My class notes on molecular genetics (and some other sources).
Basics
DNA Watson and Crick’s hypothesis had immediately suggested a possible self-replication method for DNA because of complementarity in base pairing. At this junction, possible modes of DNA replication: Conservative / Semi-conservative / Dispersive Meselson-Stahl Experiment proves replication is semi-conservative Bacteria grown in N(15) medium incorporate N14 in a light medium - CsCl density gradient centrifugation revealed. Identification of Replication Fork John Cairns identified the replication fork by allowing replicating DNA in cells to incorporate tritiated thymidine. Each daughter molecule contains a radioactive strand and a cold strand. ...